Tehran: Spokesperson for Iran's Ministry of Foreign Affairs, Esmaeil Baqaei described the talks as intensive, but said the success of negotiations depends on the seriousness and good faith of the opposing side.
Esmail Baghaei said that the Iran and the US have "reached an understanding on a number of issues" and that there were "differences of opinion on two to three important" matters.
'These negotiations were held after 40 days of imposed war and were held in an atmosphere of mistrust and suspicion. It is natural that we should not have expected from the beginning to reach an agreement within one meeting,' he said.
Earlier, Iranian state broadcaster IRIB reported that "unreasonable demands" by the United States scuppered talks in Islamabad to end the war in the Middle East.
"The Iranian delegation negotiated continuously and intensively for 21 hours in order to protect the national interests of the Iranian people; despite various initiatives from the Iranian delegation, the unreasonable demands of the American side prevented the progress of the negotiations. Thus the negotiations ended," IRIB said on Telegram.
On the other hand, Iran's Tasnim news agency citing an informed source said, "As long as the US does not agree to a reasonable deal, there will be no change in situation in Strait of Hormuz."
Various issues including Strait of Hormuz, nuclear rights have been among the points of contention in the talks, Iran's Press TV reported.
The conflict, which began on February 28 following coordinated US-Israeli strikes targeting Iran's leadership and infrastructure, has resulted in more than 2,000 deaths and widespread regional instability. Tehran responded with retaliatory operations, including the disruption of shipping through the Strait of Hormuz and attacks on Israeli and US targets in the region.
A ceasefire was eventually announced on April 8, with Pakistan playing a central role in mediation. However, key disagreements persist. Washington has proposed a 15-point framework focusing on nuclear and missile issues, sanctions relief and reopening of the Strait of Hormuz, while Tehran has presented a 10-point plan seeking greater control over the waterway, transit fees, and comprehensive sanctions removal.
The international community has broadly welcomed Pakistan's diplomatic role, backing its efforts to de-escalate tensions and facilitate negotiations aimed at achieving lasting peace.
Delegations from the two countries had arrived in Islamabad for the negotiations.
The high-powered American team, headed by Vice President JD Vance and comprising Special Envoy Steve Witkoff and President Donald Trump's son-in-law Jared Kushner, arrived in Islamabad on Saturday to participate in the negotiations.
Separately, a senior Iranian delegation led by Parliament Speaker Mohammad Baqer Ghalibaf also arrived in Islamabad ahead of the talks. The delegation includes Foreign Minister Abbas Araghchi, who is expected to play a key role in the negotiations.